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[Corticosteroid dependence and resistance in Crohn's disease: prevalence and predictive factors]
Sami Karoui1, Lamia Ben Yaghlene, Monia Fekih
1Service de Gastro-entérologie A, Hôpital la Rabta, Tunis, Tunisie.
La Tunisie Medicale
|April 24, 2003
Abstract:
The aim of our study was to determine the prevalence of corticosensibility, corticodependency, and corticoresistance in patients with Crohn's disease. Ninety four treatments with corticoids were prescribed to the patients during the follow-up. The rates of corticosensibility, corticodependency, and corticoresistance were 66%, 16%, 18%. Corticodependency and corticoresistance are frequent in Crohn's disease. Corticodependency is more frequent in young patients and when corticoids were previously taken. A high CDAI was the only factor associated with a higher risk of corticoresistance.