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Updated: Sep 26, 2026

Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents
Published on: September 10, 2018
[Cost-effectiveness analysis: a reader's guide]
1Service de l'Information Médicale et de l'Evaluation, Hôpital du Cluzeau, CHU Dupuytren, Limoges cedex, France. avergne@unilim.fr
Introduction:
This article is devoted to the critical appraisal of cost-effectiveness analysis.
Methods:
The example chosen concerns the choice of first line chemotherapy for a patient with stage IV non small cell bronchial carcinoma; a common problem in thoracic oncology. It compares three chemotherapy regimes: vinorelbine alone, cisplatin-vinorelbine and cisplatin-vindesine.
Perspectives:
The guide used allows evaluation of the validity of the methodology and, therefore, of the results obtained.
Conclusion:
The article studies the possible application of these results to the patient whose clinical history was presented as an introduction. The limitations of cost-effectiveness analyses are also considered.
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