Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electrokinetic focusing injection methods on microfluidic devices.

Lung-Ming Fu1, Ruey-Jen Yang, Gwo-Bin Lee

  • 1Department of Engineering Science, National Cheng Kung University, Tainan, 70101 Taiwan.

Analytical Chemistry
|April 26, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated circuit-microfluidic biosensors for blood-based disease diagnostics-A review.

Analytica chimica acta·2026
Same author

Rapid Finger-Pump Microfluidic Paper-Based Assay Platform for Monitoring Calcium Ions in Human Biofluids.

Biosensors·2026
Same author

Novel microfluidic gelatin-paper-based chip for sensitive colorimetric detection of urine albumin.

Analytica chimica acta·2026
Same author

Electrokinetic Microfluidics at the Convergence Frontier: From Charge-Driven Transport to Intelligent Chemical Systems.

Micromachines·2026
Same author

Microfluidic Paper-Based Devices at the Edge of Real Samples: Fabrication Limits, Hybrid Detection, and Perspectives.

Micromachines·2026
Same author

Electrochemical biosensor microchip platform for rapid whole-blood chloride ions quantification in CKD point-of-care monitoring.

Talanta·2026
Same journal

The ACS at 150: The History of Analytical Chemistry Publications and a Century of Progress.

Analytical chemistry·2026
Same journal

Machine Learning-Enabled Image Analysis of Complex Chemical Mixtures: Synthetic Urine Droplets as a Test System.

Analytical chemistry·2026
Same journal

H<sub>2</sub>O<sub>2</sub>/Viscosity Tandem-Locked Fluorescent Probes Based on an In Situ Fluorophore Synthesis Strategy for Colitis Imaging and Diagnosis.

Analytical chemistry·2026
Same journal

TopoStitcher: A Geometric-Topological Structure-Guided Stitching Framework for Single-Molecule Localization Microscopy.

Analytical chemistry·2026
Same journal

Noninvasive SERS Immunosensing of Tyrosinase for Melanoma Monitoring via Microneedle Sampling Integrated with Satellite-Structured Bifunctional Nanozymes.

Analytical chemistry·2026
Same journal

Label-Free Electrochemical CRISPR Platform Gated by Allosteric Transcription Factors for Ultrasensitive Small-Molecule Detection.

Analytical chemistry·2026
See all related articles

This study introduces a novel microfluidic chip for electrokinetic focusing injection, enabling precise control over sample plug volumes using electric potentials to create virtual valves.

Area of Science:

  • Microfluidics
  • Electrokinetics
  • Analytical Chemistry

Background:

  • Microfluidic devices offer miniaturized platforms for various analytical applications.
  • Precise control over sample manipulation is crucial for efficient microfluidic assays.
  • Traditional injection systems can be complex and occupy significant chip real estate.

Purpose of the Study:

  • To investigate electrokinetic focusing injection for precise sample plug delivery on microfluidic chips.
  • To design and test a novel double-cross injection system for variable volume sample delivery.
  • To demonstrate the use of electric potential manipulation for virtual valving in microfluidics.

Main Methods:

  • Experimental fabrication and testing of a double-cross injection microfluidic chip.

Related Experiment Videos

  • Numerical simulations to analyze fluid flow and electric field distributions.
  • Application of controlled electric potential strengths for sample loading and dispensing.
  • Utilizing electrokinetic focusing principles for sample plug formation.

    • Main Results:

    • Successful fabrication of a novel double-cross injection microfluidic chip.
    • Demonstration of electrokinetic focusing for delivering variable volume sample plugs.
    • Validation of electric potential manipulation for effective virtual valving.
    • Integration of multiple injection functions onto a single microfluidic chip.

    Conclusions:

    • The developed electrokinetic focusing injection system provides precise control over sample plug volume.
    • The novel microfluidic chip design integrates multiple functions, simplifying sample handling.
    • Electric potential manipulation offers an effective strategy for virtual valving in microfluidic systems.