Related Experiment Videos
Regioselective Sonogashira couplings of 2,4-dibromoquinolines. A correction
Jason M Nolan1, Daniel L Comins
1Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695-8204, USA.
The Journal of Organic Chemistry
|April 26, 2003
Abstract:
Heteronuclear multiple bond correlation (HMBC) was used to determine the regiochemical outcome of palladium-catalyzed carbon-carbon bond formation between 2,4-dibromoquinolines and terminal acetylenes. The observed regioselectivity of these coupling reactions is opposite to that reported in the literature for analogous reactions.