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Updated: Sep 26, 2026

Development and Validation of Chromium Getters for Solid Oxide Fuel Cell Power Systems
Published on: May 26, 2019
Sialoglycoprotein and carbohydrate complexes in chromium toxicity
Rachel Codd1, Jennifer A Irwin, Peter A Lay
1Centre for Heavy Metals Research, School of Chemistry, University of Sydney, NSW 2006, Australia.
Abstract:
Chromium(VI) compounds are amongst the most widely encountered industrial carcinogens and are of increasing concern with respect to environmental exposure. Sialoglycoproteins and carbohydrates play a crucial role in stabilizing oxoCr(V) intermediates, which are produced by extracellular and intracellular reduction of chromium(VI). Recent research has addressed the molecular characterization of oxoCr(V)-sialoglycoprotein and -carbohydrate complexes and the roles that these species may play in Cr(VI) metabolism and carcinogenesis. Particular highlights include the role of oxoCr(V) complexes of extracellular sialoglycoproteins, intracellular D-glucose, and related species and their potential roles in Cr(VI)-induced genotoxicity.
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