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Updated: Sep 26, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
Published on: January 7, 2018
[Transformation of sugar and other carbohydrates into fat in humans]
Bjørn Quistorff1, Niels Grunnet
1Københavns Universitet, Panum Instituttet, Stofskiftecentret, Institut for Medicinsk Biokemi og Genetik.
Abstract:
The basic biochemistry of de novo lipogenesis and the current understanding of fat formation from carbohydrates in humans are reviewed. The suggestion is made that ingestion of carbohydrates in excess of the caloric needs necessarily results in de novo lipogenesis since the glycogen stores are already full. Under these circumstances a formation per day of 15-20 g palmitate from carbohydrates has been reported in the liver and a similar amount in the peripheral tissues.
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