Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

"Double" potentials define linear lesion conduction block using a novel mapping/linear lesion ablation catheter.

John M Morgan1, Guy Haywood, Alexander Schirdewan

  • 1Wessex Cardiac Centre, Southampton University Hospitals, Southampton, United Kingdom. jmm@cardiology.co.uk

Journal of Cardiovascular Electrophysiology
|April 29, 2003
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rigidity Percolation Dictates Rheological Hysteresis Regime in Polypropylene during Crystallization and Melting.

Macromolecules·2026
Same author

One-Year Outcomes of the MODULAR ATP Trial: A Novel Leadless Pacemaker in Wireless Communication With a Subcutaneous Implantable Cardioverter Defibrillator.

Circulation. Arrhythmia and electrophysiology·2025
Same author

Current practices in managing patients with cardiac implantable electronic devices: Results of an international survey.

Heart rhythm O2·2025
Same author

Gene Expression Dysregulation in Whole Blood of Patients with <i>Clostridioides difficile</i> Infection.

International journal of molecular sciences·2024
Same author

Predictors of death without prior appropriate therapy in ICD recipients: the comorbidities, frailty and functional status (COMFFORT study).

Open heart·2024
Same author

Trans-septal left ventricular endocardial lead in a patient with extensive anterior myocardial infarction and left ventricle (LV) apical endoventriculoplasty using a Vascutek patch-case report.

AME case reports·2024

A novel catheter with a movable ablation electrode successfully created linear lesions for atrial flutter, demonstrating double potentials (DPs) that confirm conduction block. This method simplifies the assessment of lesion efficacy without extra mapping tools.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Atrial flutter ablation often requires precise lesion creation.
  • The cavotricuspid isthmus (CTI) is a common target for ablation in counterclockwise atrial flutter.
  • Assessing conduction block after ablation is crucial for procedural success.

Purpose of the Study:

  • To evaluate a novel mapping/ablation catheter with a coaxially movable electrode for creating linear lesions.
  • To assess the utility of bipolar electrogram recordings from this catheter in confirming conduction block across the CTI.
  • To determine if double potentials (DPs) generated during ablation correlate with bidirectional block.

Main Methods:

  • A novel catheter with a movable ablation electrode was used in 32 patients undergoing CTI ablation for atrial flutter.

Related Experiment Videos

  • Radiofrequency energy was applied in 2-mm steps to create a linear lesion.
  • Bipolar electrograms (E1, E2) were recorded between the movable electrode and fixed ring electrodes.
  • Double potentials (DPs) were observed and their interpotential distance and timing were analyzed.
  • Main Results:

    • The novel catheter successfully created linear lesions across the CTI in all patients.
    • Double potentials (DPs) were consistently observed during and after lesion creation.
    • Maximal interpotential distance of DPs correlated with complete linear lesion and bidirectional block.
    • DP interpotential timing varied depending on pacing location and heart rhythm.

    Conclusions:

    • Bipolar recordings from the coaxially movable electrode catheter provide valuable electrogram data.
    • Observed DPs during and after linear lesion creation effectively define conduction block.
    • This technique offers a simplified method for confirming lesion efficacy, reducing the need for additional mapping technologies.