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HIV and hepatitis B virus: options for managing coinfection

Douglas T Dieterich1

  • 1Mt Sinai School of Medicine, New York, NY, USA.

Topics in HIV Medicine : a Publication of the International AIDS Society, USA
|April 30, 2003
PubMed

Insights

Coinfection with HIV and hepatitis B virus (HBV) worsens HBV prognosis. Newer treatments offer hope for managing chronic HBV in coinfected patients.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Virology

Background:

  • Hepatitis B virus (HBV) infection in patients with human immunodeficiency virus (HIV) is common.
  • HBV infection in HIV-positive individuals is associated with a poorer prognosis for HBV disease compared to HIV-negative individuals.

Observation:

  • A case history of a patient coinfected with HIV and HBV was presented at the International AIDS Society-USA course in 2002.
  • The coinfection complicates the management of both viral diseases.

Findings:

  • Management of chronic HBV infection in coinfected patients presents challenges.
  • Emerging treatment options for chronic HBV infection are improving the potential for successful management.

Implications:

  • Optimizing treatment strategies for coinfected patients is crucial.
  • Further research into novel therapeutic approaches for HIV and HBV coinfection is warranted.

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