Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Churg-Strauss syndrome].

V Cottin1, J-F Cordier

  • 1Service de Pneumologie, Hôpital Louis-Pradel, Université Claude-Bernard, BP Lyon-Montchat, 69394 Lyon Cedex 03. vincent.cottin@chu-lyon.fr

Revue De Pneumologie Clinique
|April 30, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Donor to recipient age matching in lung transplantation: A European experience.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2024
Same author

Outcomes of lung transplantation for pleuroparenchymal fibroelastosis: A French multicentric retrospective study.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2024
Same author

[Genetic diffuse cystic lung disease in adults].

Revue des maladies respiratoires·2023
Same author

Alpha1-antitrypsin deficiency in Greece: Focus on rare variants.

Pulmonology·2023
Same author

[Lung transplantation for systemic sclerosis-associated interstitial lung disease].

Revue des maladies respiratoires·2023
Same author

[Updated indications and contraindications in 2022 for lung transplantation in France].

Revue des maladies respiratoires·2022

Churg-Strauss syndrome is an eosinophilic vasculitis linked to asthma and allergies. Diagnosis requires asthma, high eosinophil counts, and systemic vasculitis, often needing biopsy and immunosuppressive treatment.

Area of Science:

  • Rheumatology
  • Pulmonology
  • Pathology

Context:

  • Churg-Strauss syndrome, also known as eosinophilic granulomatosis with polyangiitis, is a rare systemic vasculitis.
  • It is strongly associated with asthma, allergic rhinitis, and prominent eosinophilia.

Purpose:

  • To summarize the key features, diagnostic criteria, and management of Churg-Strauss syndrome.
  • To highlight the respiratory and systemic manifestations of this condition.

Summary:

  • This vasculitis typically presents with severe, steroid-dependent asthma preceding systemic symptoms by years.
  • Respiratory involvement includes allergic rhinitis, nasal polyposis, and sinusitis.
  • Systemic manifestations involve gastroenteritis, neuropathy, skin lesions, kidney disease, and joint pain.

Related Experiment Videos

  • Cardiac involvement is often asymptomatic but carries a grave prognosis.
  • Diagnosis relies on clinical findings (asthma, eosinophilia >1.5 G/L, multi-organ vasculitis), ANCA positivity in 66% of cases, and histological confirmation of eosinophilic small-vessel vasculitis.
  • Treatment involves corticosteroids and immunosuppressive agents like cyclophosphamide for severe cases.

    • Impact:

    • Early recognition and diagnosis are crucial for timely intervention and improved patient outcomes.
    • Understanding the diverse clinical spectrum aids in managing this complex autoimmune disease.
    • This summary provides a concise overview for clinicians and researchers involved in diagnosing and treating Churg-Strauss syndrome.