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Updated: Jul 22, 2026

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
[HUMANS: a neuropsychological battery for evaluating HIV 1 infected patients]
A Ardila-Ardila1, K Goodkin, M Concha-Bartolini
1Departamento de Psiquiatría, Jackson Memoral/University of Miami, Miami, FL 33182, USA. alfredoardila@cs.com
Objective:
To develop a neuropsychological test battery in Spanish for the cognitive evaluation of HIV 1 infected patients.
Development:
Departing from the suggestions presented by the work group of the National Institute of Mental Health (USA), a neuropsychological assessment battery was developed. It was named HUMANS (HIV/University of Miami Annotated Neuropsychological test battery in Spanish). This battery includes the following domains: 1) attention and speed of processing information, 2) memory, 3) executive function, 4) language, 5) visuospacial/visuoconstructive abilities, and 6) motor abilities. Administration takes about 3 4 hours. The English parallel version of this battery has been successfully used in English for over a decade with HIV 1 infected patients. In the paper the development and adaptation to Spanish language of the HUMANS neuropsychology section is presented.
Conclusions:
HUMANS neuropsychological test battery fulfill the recommendations presented by the work group of the National Institute of Mental Health for evaluating HIV 1 infected patients. Studies regarding validity and reliability are still required.

