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Response of Cervical Intra-epithelial Lesions to Vitamin E Supplementation - A Preliminary Report
Chaiti Ganguly1, Karabi Dutta, Utpal Sanyal
1Dept. of Cancer Chemoprevention, Chittaranjan National Cancer Institute, Kolkata 700026, India.
Abstract:
Carcinoma of the uterine cervix is preceded by well characterized pre-cancerous lesions which if left untreated may progress to invasive carcinoma. In the present study women in the age group of 35-55 years with cervical intraepithelial lesions (CIN I & II) were treated with vitamin E and advised to come for follow up after every three months for one year. This preliminary report shows vitamin E can restrict and regress CIN I & II lesions with elevation in circulating vitamin E levels. Improvement in immune status as reflected in mitogenic responses of peripheral blood lymphocytes was also noted.

