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Appendicitis in infancy
1Division of Pediatric Surgery, Changhua Christian Hospital, No.135 Nanhsiau Street, Changhua, Taiwan, Republic of China. 73654@cch.org.tw
Insights
Diagnosing acute appendicitis in infants is challenging due to non-specific symptoms. This study highlights high morbidity and a significant Pseudomonas aeruginosa infection rate in infantile appendicitis cases.
Area of Science:
- Pediatric Surgery
- Infant Health
- Infectious Diseases
Background:
- Acute appendicitis is common in children but rare in infants.
- Infantile appendicitis presents with non-specific signs and symptoms, complicating early diagnosis.
- Delayed diagnosis can lead to severe complications and increased morbidity.
Purpose of the Study:
- To review cases of acute appendicitis in infants treated over a 10-year period.
- To analyze clinical presentation, diagnostic delays, and outcomes.
- To investigate the prevalence of Pseudomonas aeruginosa infections in this population.
Main Methods:
- Retrospective review of 7 infant cases (17 days to 8 months) diagnosed with acute appendicitis.
- Analysis of preoperative symptoms, signs, duration to surgery, pathology reports, and laboratory data.
- Microbiological cultures from blood, ascites, bile, or stool were examined.
Main Results:
- No specific clinical indicators were identified for early diagnosis.
- The average time from admission to operation was 31.4 hours.
- Pathology revealed 3 gangrenous, 3 gangrenous with perforation, and 1 suppurative appendicitis.
- One infant death occurred.
- Pseudomonas aeruginosa was identified in 6 out of 7 cases (85.7%).
Conclusions:
- Early diagnosis of acute appendicitis in infants remains difficult.
- Morbidity rates for infantile appendicitis are high, despite declining mortality.
- The high incidence of Pseudomonas aeruginosa warrants further investigation in infantile appendicitis.
Abstract:
Acute appendicitis is the most common cause of abdominal pain requiring surgery in children. But it is an uncommon entity in young children and rare in infants. During a 10-year period, between January 1991 and December 2000, 7 infants (age from 17 days to 8 months) were treated for acute appendicitis at Changhua Christian Hospital. All of the preoperative symptoms and signs, the duration between admission and operation, pathology reports, and laboratory data were reviewed. There were no specific clinical signs and symptoms. The duration between admission and operation ranged from 2 hours to 5 days (mean: 31.4 hours). The pathology reports revealed 3 were gangrenous, 3 were gangrenous with perforation and one was suppurative. There was one death. Pseudomonas aeruginosa was cultured from blood, ascites, bile or stool in 6 cases (85.7%). Early diagnosis of acute appendicitis in infants is still difficult. Although the mortality has declined, the morbidity still remains high. The high percentage of infection by Pseudomonas aeruginosa should be further evaluated in infantile appendicitis.
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