Related Experiment Video
Updated: Sep 26, 2026

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Investigation of host-guest stability constants of calix[n]arenes complexes with aromatic molecules by RP-HPLC method
R Baudry1, O Kalchenko, I Dumazet-Bonnamour
1Laboratoire de Chimie Industrielle, CNRS-UMR 5078, Université Claude Bernard-Lyon1, 43, Bd du 11 Novembre 1918, 69622 Villeurbanne Cedex, France.
Abstract:
Under reversed-phase high-performance liquid chromatographic conditions [Spherisorb ODS 1 stationary phase, UV detection at 254 nm, and acetonitrile-dichloromethane-acetic acid-methyl-tert-butylether (84.6/4.5/0.9/10, v/v/v/v) as the mobile phase], adding p-tert-butylcalix[8] (10(-5)-3.10(-5))-[12]arenes (10(-5)-4.10(-5) mol/L) to the mobile phase leads to decreased sorption of aromatic solutes on the surface of the sorbent because of the formation of host-guest inclusion complexes between the calixarenes and the aromatic molecules. Stability constants of the complexes (781-9338M(-1)) are determined from the relationship between the solute capacity factors and the calixarene concentration in the mobile phase.
More Related Videos
Related Concept Videos
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
NMR Spectroscopy of Aromatic Compounds
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
¹H NMR: Long-Range Coupling
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene π orbitals.
IR Frequency Region: Alkyne and Nitrile Stretching
Comparing the stretching vibrational frequency of C≡C triple bonds with that of double and single bonds, it is evident that C≡C triple bonds exhibit a higher stretching frequency than C=C double and C–C single bonds. Similarly, the C≡N triple bond exhibits higher stretching absorption than the C=N...
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

