[Topical fibrinolysis with streptokinase in coagulated hemothorax]

Local fibrinolysis using streptokinase was used in two patients with an organizing extensive haemothorax. In both patients the coagula were dissolved and the pleural cavity was effectively evacuated by means of a drain without the necessity of an extensive surgical intervention. The authors did not record any side-reactions to the local administration of streptokinase. In the authors' opinion proper timing is important for achieving a satisfactory effect of local fibrinolysis. Fibrinolysis cannot be used in case of clinical signs of proceeding haemorrhage or closely after its termination.