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Identification of 2-aminobenzimidazole dimers as antibacterial agents
Punit P Seth1, Elizabeth A Jefferson, Lisa M Risen
1Ibis Therapeutics, A Division of Isis Pharmaceuticals, Inc., 2292 Faraday Avenue, Carlsbad, CA 92008, USA. pseth@isisph.com
Bioorganic & Medicinal Chemistry Letters
|May 6, 2003
Abstract:
The preparation and evaluation of 2-aminobenzimidazole dimers as antibacterial agents is described. Biological screening of the dimers indicated that compounds with multiple chloro substituents possessed optimal antibacterial activity.