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[Pancreatic insulinomas].

F Ticmeanu1, S Simion, A Croitoru

  • 1Clinica de Chirurgie Colentina Bucureşti.

Chirurgia (Bucharest, Romania : 1990)
|May 7, 2003
PubMed
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Surgical treatment is the most effective therapy for insulinomas, a generally benign pancreatic tumor. This study reviewed 18 patients, highlighting surgical approaches and outcomes.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Gastroenterology

Context:

  • Insulinomas are rare pancreatic neuroendocrine tumors.
  • Diagnosis and management can be challenging due to varied presentations.
  • Surgical intervention is the primary treatment modality.

Purpose:

  • To evaluate the surgical management and outcomes of histopathologically confirmed insulinomas.
  • To analyze the efficacy of different surgical approaches and their impact on patient recovery.

Summary:

  • A 20-year study (1980-1999) at "Colentina" Surgical Clinic involved 18 patients (8 males, 10 females) with insulinomas.
  • Tumor locations varied, with most in the body and tail of the pancreas.
  • Surgical treatments included enucleation, corporeal-caudal pancreatico-splenectomy, and cephalic pancreatico-duodenectomy.

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  • Malignancy was confirmed in 30% of cases, with postoperative mortality in 3 cases due to acute pancreatitis, MSOF, and myocardial infarction.

    • Impact:

    • Surgical resection remains the most effective therapy for insulinomas.
    • Understanding tumor topography and clinical presentation aids in surgical planning.
    • This study contributes to the understanding of surgical outcomes for insulinoma patients.