Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Merkel cell carcinoma].

T Burcoş, E Popa, A Ivăşcanu

    Chirurgia (Bucharest, Romania : 1990)
    |May 7, 2003
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Laparoscopic anatomical landmarks in oncological dissection for low rectal cancers - a video vignette.

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2020
    Same author

    Occurrence and significance of vascular invasion in multinodular adenomatous goiter.

    Endocrine pathology·2020
    Same author

    Professor Doctor Nicolae Angelescu.

    Chirurgia (Bucharest, Romania : 1990)·2016
    Same author

    Prophylactic Percutaneous Endoscopic Gastrostomy (PEG) - The Importance of Nutritonal Support in Patients with Head and Neck Cancers (HNCs) or Neurogenic Dysphagia (ND).

    Chirurgia (Bucharest, Romania : 1990)·2015
    Same author

    The role of immunohistochemical tests in multimodal treatment of the aggressive forms of breast cancer.

    Journal of medicine and life·2015
    Same author

    CT vs. MRCP in choledocholithiasis jaundice.

    Journal of medicine and life·2015
    Same journal

    From Scope to Scalpel: A Review of the Timing and Outcomes of Conversion in Minimally Invasive Liver Resections.

    Chirurgia (Bucharest, Romania : 1990)·2026
    Same journal

    Pediatric Penetrating Foot Injury Complicated by Soft-Tissue Infection.

    Chirurgia (Bucharest, Romania : 1990)·2026
    Same journal

    Laparoscopic Removal of a Gastric Trichobezoar in Adulthood: A Case Report.

    Chirurgia (Bucharest, Romania : 1990)·2026
    Same journal

    Metabolomic Profiling of Plasma Bile Acids in Resectable Gastric Cancer.

    Chirurgia (Bucharest, Romania : 1990)·2026
    Same journal

    Laparoscopic Surgery: Patient Benefits and Surgeon Challenges. A Systematic Literature Review and Narrative Synthesis.

    Chirurgia (Bucharest, Romania : 1990)·2026
    Same journal

    Erratum to Laparoscopic Pancreaticoduodenectomy - Initial Experience in a Hepatopancreatobiliary High-Volume Center.

    Chirurgia (Bucharest, Romania : 1990)·2026
    See all related articles

    Merkel Cell Carcinoma (MCC) is a rare, aggressive skin cancer. This analysis of two cases highlights challenges in diagnosis and treatment, noting high recurrence rates despite aggressive therapies.

    Area of Science:

    • Dermatology
    • Oncology
    • Pathology

    Background:

    • Merkel Cell Carcinoma (MCC) is a rare neuroendocrine skin cancer, often found on sun-exposed areas.
    • Diagnosis requires clinical evaluation, microscopy, and specific immunohistochemical markers (cytokeratins, neuron-specific enolase, chromogranin).
    • MCC exhibits aggressive behavior with high rates of local, regional, and distant spread.

    Observation:

    • This study presents a retrospective analysis of two MCC cases.
    • Data includes clinical presentation, histopathology, immunohistochemistry, and treatment outcomes.
    • Treatment involved surgery, chemotherapy, and radiotherapy.

    Findings:

    • MCC is characterized by aggressive local or locoregional extension and distant metastasis via hematogenous or lymphatic routes.

    Related Experiment Videos

  • Surgical excision and lymphadenectomy are primary treatments, often combined with radiotherapy and chemotherapy.
  • Despite treatment, high rates of local or distant recurrence were observed.

    • Implications:

    • Early and accurate diagnosis of Merkel Cell Carcinoma is crucial.
    • Multimodal treatment approaches are necessary for managing this aggressive neoplasm.
    • Further research is needed to improve outcomes and reduce recurrence rates for MCC patients.