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Liposarcoma presenting as an intraluminal ureteral mass
Ganesh V Raj1, John F Madden, E Everett Anderson
1Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.
Urology
|May 9, 2003
Summary
Recurrent liposarcoma can aggressively obstruct the ureter, leading to kidney damage. Despite surgical removal and clear margins, this aggressive tumor rapidly recurred, resulting in patient death.
Area of Science:
- Oncology
- Urology
- Pathology
Background:
- Liposarcoma is a malignant tumor arising from fat cells.
- Retroperitoneal liposarcomas can be challenging to manage due to their location and potential for recurrence.
Observation:
- An 86-year-old woman with a history of retroperitoneal liposarcoma presented with flank discomfort.
- Imaging revealed left hydronephrosis caused by an intraluminal ureteral tumor, identified as recurrent liposarcoma.
Findings:
- The patient underwent a nephroureterectomy for palliation of the obstructing tumor.
- Pathologic examination confirmed high-grade liposarcoma.
- Despite negative surgical margins, the tumor recurred rapidly, leading to death within 4 months.
Implications:
- This case underscores the aggressive behavior of some liposarcoma subtypes.
- Intraluminal ureteral recurrence of liposarcoma is a rare but critical presentation.
- Aggressive surveillance and management strategies may be necessary for high-grade liposarcomas.