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Published on: August 29, 2010
Oral contraceptives improve lung mechanics
Tomislav Strinić1, Davor Eterović
1Department of Obstetrics and Gynecology, University Hospital Split, Split, Croatia.
Objective:
To determine whether oral contraceptives affect lung mechanics.
Design:
Open-label study.
Setting:
Academic medical center.
Patient(S):
Thirty-six healthy nonsmoking women.
Intervention(S):
Administration of an oral contraceptive containing ethinyl estradiol, 35 microg, and norgestimat, 250 microg for 6 months.
Main Outcome Measure(S):
Forced vital capacity; forced expiratory volume in 1 second; peak expiratory flow; and flow at large, medium, and small lung volumes.
Result(S):
At 6 months, all forced expiratory flow and volume had increased significantly (from 6.5% to 15%). Flows at small lung volumes especially increased.
Conclusion(S):
Combination oral contraceptives have a measurable effect on lung mechanics.
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