Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Heart rate variability in cluster headache.

Luigi Tubani1, Luigi Baratta, Flavia Giorgino

  • 1Dipartimento di Medicina Clinica, Università degli Studi La Sapienza di Roma.

Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|May 13, 2003
PubMed
Summary

Cluster headache attacks reveal significant autonomic nervous system imbalance, with altered parasympathetic and sympathetic drive during episodes. Patients also show reduced low-frequency heart rate variability between attacks, suggesting dysfunction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expanded phylogeny elucidates Deinosuchus relationships, crocodylian osmoregulation and body-size evolution.

Communications biology·2025
Same author

Can a "broken heart" successfully be transplanted? A brief report.

Clinical transplantation·2024
Same author

World's oldest heart transplant donor: age is just a number.

Journal of cardiovascular medicine (Hagerstown, Md.)·2024
Same author

Cryoglobulinemia: the "cold" problem in cardiac surgery, a single-center experience and a literature review.

Journal of anesthesia, analgesia and critical care·2024
Same author

Heart transplant in a Sars-CoV-2 positive recipient: Management protocol of the world's first case.

Clinical transplantation·2023
Same author

Biogeographic history of Palearctic caudates revealed by a critical appraisal of their fossil record quality and spatio-temporal distribution.

Royal Society open science·2022

Area of Science:

  • Neurology
  • Cardiology
  • Autonomic Neuroscience

Background:

  • Cluster headache is a debilitating neurological disorder.
  • Autonomic nervous system (ANS) dysfunction is suspected in its pathophysiology.
  • Heart rate variability (HRV) analysis offers insights into ANS activity.

Purpose of the Study:

  • To investigate ANS function in cluster headache patients.
  • To evaluate HRV during cluster headache attacks (critic periods) and headache-free periods (intercritic periods).
  • To compare patient HRV with healthy controls.

Main Methods:

  • 24-hour ECG monitoring in 8 cluster headache patients.
  • Analysis of HRV parameters during spontaneous attacks and intercritic periods.
  • Comparison of patient data with normal control subjects.

Related Experiment Videos

Main Results:

  • Severe sympathovagal imbalance observed during cluster headache attacks.
  • Increased parasympathetic drive and reduced sympathetic drive at attack onset.
  • Significant reduction in low-frequency HRV values during intercritic periods in patients.
  • These HRV changes suggest underlying ANS dysfunction.

Conclusions:

  • Cluster headache is associated with significant autonomic nervous system dysfunction.
  • Specific HRV alterations occur during and between attacks.
  • Findings support a role for ANS dysregulation in cluster headache pathophysiology.