Related Experiment Videos
Nitrophenol resins for facile amide and sulfonamide library synthesis
Jae Wook Lee1, Ying Qi Louie, Daniel P Walsh
1Department of Chemistry, New York University, New York, New York 10003, USA.
Journal of Combinatorial Chemistry
|May 13, 2003
Abstract:
Novel nitrophenol solid supports based on various resin materials (polystyrene, TentaGel, macroporous, PEGA, and silica gel) are reported for facile amide and sulfonamide library synthesis. The broad choice of resin materials available will allow the reaction to occur successfully in solvents ranging from nonpolar organic solvents to aqueous media.