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Updated: Jul 29, 2026
Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
[Energy metabolism of blood lymphocytes after insertion of titanium implants]
E B Saranchina1, A G Loginov, V N Gorchakov
1Department of Orthopedic Stomatology, Novosibirsk State Medical Academy, Laboratory of Functional Morphology of Lymphatic System, Scientific Research, Novosibirsk.
Abstract:
Blood lymphocyte dehydrogenase activity (SDH, LDH, mitochondrial and cytoplasmic alpha-glycerophosphate dehydrogenase, NADH-diaphorase) was studied in 140 Wistar rats at different time intervals following intraosseous insertion of titanium implants. It was shown that implantation was accompanied with an increase in enzyme activities indicating a rise in the intensity of energy production processes. Cytochemical analysis of lymphocyte enzymes enables to formulate a "prognostic scenario" describing titanium implant interaction with biological environmental factors and organism tissues to assess the long-term results of implantation.
