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Updated: Jul 19, 2026
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Summary, conclusions and recommendations: adverse temperature levels in the human body
L S Goldstein1, M W Dewhirst, M Repacholi
1Radiation Studies Program, World Health Organization, 20, Avenue Appia, CH-1211, Geneva 27, Switzerland. goldsteinl@who.int
Summary
Scientists reviewed hyperthermia effects from radiofrequency (RF) radiation (10-300 GHz). They concluded that safe exposure standards should consider both temperature and duration of exposure.
Area of Science:
- Environmental Health
- Biophysics
- Toxicology
Background:
- Radiofrequency (RF) electromagnetic radiation standards (10-300 GHz) are currently based on thermal effects.
- Hyperthermia, or elevated body temperature, can impact human physiology and health.
- Understanding adverse temperature effects is crucial for setting safe exposure limits.
Purpose of the Study:
- To review evidence on adverse effects of hyperthermia from RF exposure (10-300 GHz).
- To inform the scientific basis for establishing safe RF exposure levels.
- To evaluate risks to human physiology, organs, and developing embryos/fetuses.
Main Methods:
- A World Health Organization workshop convened experts in biological effects of hyperthermia.
- Data on physiological, cognitive, and tissue damage from hyperthermia were reviewed.
- Studies were assessed for relevance to decision-makers on RF exposure safety.
Main Results:
- Hyperthermia affects physiology, thermoregulation (e.g., sweating), and cognitive performance.
- Heat-related disorders (e.g., heat stroke) and tissue damage are risks associated with elevated temperatures.
- Thresholds for effects on developing embryos/fetuses and potential carcinogenicity were examined.
Conclusions:
- Safe RF exposure standards should integrate both temperature and time of exposure.
- Cellular and biochemical responses to hyperthermia provide context for risk assessment.
- Expert consensus emphasized a dual approach for setting safety guidelines.
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