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[Sepsis: our series]

P. Bellissima1, R. Amato

  • 1U.O. di Malattie Infettive e Servizio di Microbiologia, Azienda Ospedaliera Gravina di Caltagirone, Catania, Italy.

Le Infezioni in Medicina
|May 16, 2003
PubMed
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Sepsis, a persistent bacteremia, can lead to septic shock. This study analyzed 186 sepsis cases, highlighting high mortality rates even with intensive care and antibiotic treatments.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Clinical Microbiology

Background:

  • Sepsis, defined as persistent bacteremia with significant symptoms, retains clinical relevance.
  • A recent definition emphasizes sepsis as a systemic inflammatory response to infection, aiding understanding of host reactions and shock prevention.

Purpose of the Study:

  • To analyze clinical cases of sepsis with positive hemoculture.
  • To focus on elderly patients (>61 years) and those admitted to the Intensive Care Unit (ICU).
  • To describe specific cases like toxic shock syndrome and bacterial endocarditis.

Main Methods:

  • Retrospective analysis of 186 sepsis cases with positive hemoculture.
  • Data collected from Caltagirone Hospital over 15 years.

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  • Inclusion of patient demographics, clinical isolates, and ICU admissions.

    • Main Results:

    • 186 patients (117 males, 69 females) were analyzed.
    • Focus on patients over 61 years old and ICU admissions.
    • Mortality rate for septic shock was approximately 30% despite comprehensive treatment.

    Conclusions:

    • Sepsis remains a critical condition with significant mortality.
    • Effective antibiotic and supportive therapies, including ICU care, are crucial but do not eliminate the risk of death.
    • Further research into sepsis management and prevention is warranted.