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Antifertility effects of Ricinus communis (Linn) on rats
K Sandhyakumary1, R G Bobby, M Indira
1Department of Biochemistry, University of Kerala, Kariavattom, Trivandrum-695581, India.
Phytotherapy Research : PTR
|May 16, 2003
Abstract:
The antifertility effects of 50% ethanol extracts of Ricinus communis have been studied in male rats. There was a drastic reduction in the epididymal sperm counts. Alteration in the motility, mode of movement and morphology of the sperms were observed. Reductions in the fructose and testosterone levels were suggestive of reduced reproductive performance. Reversibility tests showed that the antifertility effect of Ricinus communis was completely reversible on withdrawal of the drug. The ethanol extracts of Ricinus communis did not cause any hepatotoxicity since the hepatic GOT and GPT levels were unaltered.