Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Continuous renal replacement therapy: does technique influence electrolyte and bicarbonate control?

H Morimatsu1, S Uchino, R Bellomo

  • 1Department of Intensive Care and Department of Medicine, Austin & Repatriation Medical Centre, Melbourne, Victoria, Australia.

The International Journal of Artificial Organs
|May 22, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

sRAGE: a prognostic factor for mortality in end-stage renal disease patients on dialysis.

Journal of biological regulators and homeostatic agents·2019
Same author

Elevated Levels of Procalcitonin and Interleukin-6 are Linked with Postoperative Complications in Cardiac Surgery.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society·2017
Same author

Nonvitamin K-dependent oral anticoagulants (NOACs) in chronic kidney disease patients with atrial fibrillation.

Thrombosis research·2017
Same author

Pathophysiology of the cardio-renal syndromes types 1-5: An uptodate.

Indian heart journal·2017
Same author

The Dose Response Multicentre Investigation on Fluid Assessment (DoReMIFA) in critically ill patients.

Critical care (London, England)·2016
Same author

Sudden cardiac death and chronic kidney disease: From pathophysiology to treatment strategies.

International journal of cardiology·2016

Continuous renal replacement therapy (CRRT) techniques impact electrolyte balance differently. Continuous veno-venous hemodiafiltration (CVVHDF) better controls serum sodium, while continuous veno-venous hemofiltration (CVVH) is linked to less metabolic acidosis and more alkalosis.

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Intensive Care Unit Management

Background:

  • Continuous renal replacement therapy (CRRT) encompasses various techniques.
  • Different CRRT modalities may influence electrolyte and acid-base homeostasis.
  • Acute renal failure (ARF) in critically ill patients necessitates effective CRRT.

Purpose of the Study:

  • To compare the efficacy of continuous veno-venous hemodiafiltration (CVVHDF) versus continuous veno-venous hemofiltration (CVVH).
  • To evaluate the impact of CVVHDF and CVVH on serum sodium, potassium, and bicarbonate control in critically ill ARF patients.

Main Methods:

  • Retrospective controlled study conducted in two tertiary intensive care units.
  • Analysis of daily serum sodium, potassium, and arterial bicarbonate levels in 99 critically ill ARF patients (49 on CVVHDF, 50 on CVVH).

Related Experiment Videos

  • Data collected before and up to two weeks after CRRT initiation, with statistical comparisons.

    • Main Results:

    • CVVHDF demonstrated superior control of serum sodium concentrations compared to CVVH (74.1% vs. 62.9%).
    • Both techniques effectively reduced serum potassium levels within 48 hours, with similar normalization rates overall.
    • CVVH was associated with a significantly lower incidence of metabolic acidosis (13.8% vs. 34.5%) and a higher incidence of metabolic alkalosis (38.9% vs. 1.1%) compared to CVVHDF.

    Conclusions:

    • CRRT techniques significantly influence electrolyte and acid-base management in critically ill patients.
    • CVVHDF offers better serum sodium control, whereas CVVH may be preferred to mitigate metabolic acidosis risk.