Carbamazepine-related hyponatremia following cardiopulmonary bypass
Theodore Velissaris1, Clinton T Lloyd, Marcus P Haw
1Wessex Cardiothoracic Centre, Southampton General Hospital, Southampton, United Kingdom. theovelissaris@hotmail.com
Abstract:
A 67-year-old man on long-term carbamazepine therapy underwent elective coronary artery bypass grafting. Following an initially uncomplicated recovery, he developed symptomatic hyponatremia. The symptoms and biochemical abnormality improved after gradual discontinuation of carbamazepine. We discuss the association between carbamazepine and hyponatremia and the causes of hyponatremia after cardiopulmonary bypass. Surgeons should consider stopping carbamazepine before operations with cardiopulmonary bypass.
Related Concept Videos
Antihypertensive Drugs: Potassium-Sparing Diuretics
Antiepileptic Drugs: Sodium Channel Blockers
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
Cardiac Catheterization I: Pre-Procedure Overview
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Hemodialysis II: Procedure and Complications
Cytotoxic Edema: Pathophysiology


