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Updated: Aug 9, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
[Classification of tumors of the blood systems--hemoblastoses]
Abstract:
The article presents a review of new concepts of pathogenesis of leukemia and changes in the schemic of hemopoiesis, which lead to the need to re-examine the existing classification of leukemia. In view of the fact that histogenetic independence of stromal and hemopoietic elements has been proved, there is no need any more for the generalizing term "reticulosis". The authors substantiate the need for differentiation between some acute an chronic leukemias and to consider them as independent nosological forms grouped according to morphological and pathogenetic characteristics and a specific treatment required. These forms, for example, include acute lymphoblast leukemia in children, among acute leukemias - hair cell leukemia, and among chronic leukemias- diseases of heavy chains. Criteria for their identification, as well as probable sources of separate forms of leukemias are described.
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