[Acute renal failure in the so-called myorenal syndrome]

Post-mortem morphological studies of the kidneys from 2 patients, who due to complications occurring in the post-operative period (operation cryothalamectomy) developed the myorenal syndrome and acute renal insufficiency, were carried out. Changes were noted in all parts of the nephron, stroma and vessels of the kidneys. The most characteristic of the myorenal syndrome was accumulation of a great number of pigmental cylinders in the lower parts of the nephrom with focal delatation of the departments located above. In pathogenesis of acute renal insufficiency in the myorenal syndrome along with impairment of the renal hemodynamics a mechanical block of the tubules with decomposition products of myoglobin is also of importance.