Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cutaneous leishmaniasis].

C D Enk1, K Gardlo, M Hochberg

  • 1The Hadassah-Germany Skin Center, Department of Dermatology, The Hebrew University Medical School, Jerusalem, Isreal. enk@hadassah.org.il

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|May 22, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental quantum speed-up in reinforcement learning agents.

Nature·2021
Same author

Real-life experience in the treatment of solar urticaria: retrospective cohort study.

Clinical and experimental dermatology·2019
Same author

Coronary stent restenosis and the association with allergy to metal content of 316L stainless steel.

Cardiovascular journal of Africa·2018
Same author

Harmonising measures of knee and hip osteoarthritis in population-based cohort studies: an international study.

Osteoarthritis and cartilage·2018
Same author

Knee tissue lesions and prediction of incident knee osteoarthritis over 7 years in a cohort of persons at higher risk.

Osteoarthritis and cartilage·2017
Same author

Pyoderma gangrenosum along superficial vein thrombosis during pregnancy.

Clinical and experimental dermatology·2015
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Leishmaniasis is a sandfly-transmitted protozoan disease affecting millions annually. Current treatments exist but an effective vaccine remains unavailable.

Area of Science:

  • Infectious Diseases
  • Parasitology
  • Tropical Medicine

Background:

  • Leishmaniasis is a significant vector-borne protozoan disease transmitted by sandflies.
  • It affects macrophages and presents primarily as cutaneous or mucocutaneous leishmaniasis.
  • Incidence approaches 2 million new cases yearly, predominantly in the Old World.

Purpose of the Study:

  • To provide an overview of leishmaniasis, including its transmission, clinical presentation, diagnosis, and treatment options.
  • To highlight the current therapeutic landscape and the absence of a vaccine.

Main Methods:

  • Review of existing literature on leishmaniasis epidemiology, pathology, and clinical management.
  • Synthesis of information on diagnostic techniques and available treatment modalities.

Related Experiment Videos

Main Results:

  • Cutaneous leishmaniasis causes characteristic skin ulcers, while mucocutaneous leishmaniasis affects mucous membranes.
  • Diagnosis is confirmed by identifying amastigotes in slit-skin smears.
  • Various systemic and topical treatments are available, including antimonials, amphotericin B, and azoles.

Conclusions:

  • Leishmaniasis remains a major global health concern with diverse clinical manifestations.
  • Effective treatment options exist, but diagnosis and accessibility can be challenging.
  • The development of an effective vaccine is a critical unmet need for disease control.