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LASIK vs LASEK vs PRK: advantages and indications
Renato Ambrósio1, Steven Wilson
1Department of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Seminars in Ophthalmology
|May 22, 2003
Summary
Laser eye surgery offers PRK and LASIK options. LASIK is dominant due to faster recovery and fewer complications, while PRK suits mild corrections and specific patient needs. LASEK is a newer PRK modification requiring further study.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Excimer laser technology revolutionized refractive surgery.
- Photorefractive keratectomy (PRK) and Laser in situ keratomileusis (LASIK) are key excimer laser procedures.
- LASIK is the current leading procedure, offering advantages over PRK.
Purpose of the Study:
- To compare the advantages and disadvantages of LASIK, PRK, and the newer LASEK procedure.
- To highlight the benefits of LASIK, including improved patient comfort and reduced complications.
- To discuss the continued relevance of PRK for specific patient groups and the emerging role of LASEK.
Main Methods:
- Review of existing literature and clinical practices comparing PRK, LASIK, and LASEK.
- Analysis of outcomes related to corneal epithelium preservation, visual recovery, wound healing, and complications.
- Consideration of patient-specific factors influencing procedure choice.
Main Results:
- LASIK offers superior early post-operative comfort, faster visual recovery, and reduced haze compared to PRK.
- PRK remains a viable option for mild-moderate corrections, thin corneas, and high-risk individuals.
- LASEK, a modified PRK, shows potential benefits but requires further clinical validation.
Conclusions:
- LASIK is the dominant refractive surgery due to its favorable outcomes.
- PRK and LASEK remain important alternatives for specific indications.
- Further research is needed to fully establish the long-term efficacy and benefits of LASEK.

