Measuring of ocular wavefront aberration in large pupils using OPD-scan

Wavefront analysis using a scanning slit refractometer (the OPD-Scan) was evaluated in both artificial and human eyes, in comparison with the Hartmann-Shack wavefront sensor (H-S) currently often used. Comparison of different methods and configurations carried out in the artificial eyes yielded basically the same results in moderate refractive error cases. There was a closer match between the RMS (root mean square) wavefront error obtained by OPD-Scan and H-S in the 6 mm pupils than in the 4 mm pupils of the same normal human eyes. Although OPD-Scan employs a different approach in determining aberration, the aberration value is similar to that of H-S, especially in large pupils.