Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Differentiating tuberculous from malignant pleural effusions: a scoring model.

José Manuel Porcel1, Manuel Vives

  • 1Department of Internal Medicine, Arnau de Vilanova University Hospital, Lleida, Spain. jporcelp@medynet.com

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|May 23, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social determinants of health: a priority for internal medicine. Position statement of the Spanish Society of Internal Medicine (SEMI) and the Portuguese Society of Internal Medicine (SPMI).

Revista clinica espanola·2026
Same author

Diagnosis and Treatment of Pleural Effusion. Recommendations of the Spanish Society of Pulmonology and Thoracic Surgery. Update 2022.

Archivos de bronconeumologia·2022
Same author

Pleural mesothelioma.

Medicina clinica·2022
Same author

Sneeze-induced chylothorax.

Archivos de bronconeumologia·2021
Same author

Sneeze-Induced Chylothorax.

Archivos de bronconeumologia·2021
Same author

Review of Medical Therapy in the Emergency Department.

Revista clinica espanola·2020
Same journal

Synergistic Effects of AI-Driven Remote Respiratory Rehabilitation and Cervical Stabilization Exercises on Forward Head Posture, Neck Pain, and Respiratory Function in Older Adults: A Randomized Controlled Trial.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development Accelerates.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Advances in Remote Monitoring Technology Applications in Anesthesia: A Narrative Review.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Muscle-Specific Differences in Neuromuscular Block and Quantitative Neuromuscular Monitoring: A Narrative Review.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Preventing Ventilator-Associated Pneumonia: A Multicenter Cross-Sectional Study of Knowledge, Attitudes, and Practices of Medical Staff in Chinese Hospitals.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Migraine in the Corporate Sector: Prevalence, Risk Factors, Job Efficiency Impact, and Management Strategies.

Medical science monitor : international medical journal of experimental and clinical research·2026
See all related articles

A new scoring system aids in differentiating tuberculous from malignant pleural effusions using clinical data and pleural fluid analysis. This simple score improves diagnostic accuracy for these often-confused conditions.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Oncology

Background:

  • Tuberculous and malignant pleural effusions share similar clinical and laboratory features, complicating diagnosis.
  • Accurate differentiation is crucial for appropriate patient management and treatment.

Purpose of the Study:

  • To develop a simple clinical score for the differential diagnosis of tuberculous versus malignant pleural effusions.
  • To evaluate the diagnostic performance of the proposed scoring system.

Main Methods:

  • A retrospective analysis of 106 patients with tuberculous pleurisy and 286 with malignant effusions.
  • Multivariate analysis incorporating clinical and laboratory variables, including adenosine deaminase, to create two scoring models.
  • Calculation of sensitivity, specificity, and ROC curves for each model.

Related Experiment Videos

Main Results:

  • Model 1 (including adenosine deaminase) identified age, temperature, pleural fluid red blood cell count, and adenosine deaminase levels as predictors.
  • Model 2 (excluding adenosine deaminase) included history of malignancy, pleural protein, and pleural fluid to serum lactate dehydrogenase ratio.
  • Both models demonstrated high sensitivity (95-97%) and specificity (91-94%) in differentiating the effusions, with high areas under the ROC curve (0.987 and 0.982).

Conclusions:

  • A score-based model combining clinical data and pleural fluid chemistry effectively differentiates tuberculous from malignant effusions.
  • The developed scoring systems offer a practical tool for improving diagnostic accuracy in challenging cases.