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Updated: Sep 26, 2026

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis
Published on: December 9, 2022
Acetylenic acids from the aerial parts of Nanodea muscosa
N El-Jaber1, A Estévez-Braun, A G Ravelo
1Instituto Universitario de Bio-Orgánica Antonio González-González, Avenida Astrofísico Fco. Sánchez No. 2, La Laguna, 38206 Tenerife, Spain.
Abstract:
The aerial parts of Nanodea muscosa, collected in Chile, yielded two new acetylenic acids. Their structures were elucidated by spectroscopic analyses, including 2D NMR techniques, as (13E)-octadec-13-en-11-ynoic acid (1) and (2E)-octadec-2-en-4-ynedioic acid (2). Compound 2 constitutes the first example of a conjugated ene-yne fatty diacid isolated from a natural source. Compounds 1 and 2 did not exhibit toxicity toward a panel of DNA damage checkpoint defective yeast mutants or show affinity for the 5-HT(1A), 5-HT(2A), D(2), and H(1) receptors.
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