Related Experiment Videos
The antiplatelet aggregation effects of aspirin suppositories
Hiroyuki Nakayasu1, Masanobu Maeda, Takao Soda
1Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan.
Cerebrovascular Diseases (Basel, Switzerland)
|May 27, 2003
Abstract:
To confirm that aspirin suppositories are an effective treatment for acute ischemic stroke, we examined the suppressive effects of 200-mg aspirin suppositories on platelet aggregation. Aspirin suppositories suppressed platelet aggregation induced by ADP or collagen, and the suppression continued for 24 h. There was no significant difference in suppression of platelet aggregation between aspirin administered by suppository and orally given aspirin. These results suggest that aspirin suppositories are a useful treatment for acute ischemic stroke.