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Marine natural products as lead anti-HIV agents

D J Gochfeld1, K A El Sayed, M Yousaf

  • 1Department of Pharmacognosy and the National Center for Natural Products Research, School of Pharmacy, P.O. Box 1848, The University of Mississippi, University, MS 38677, USA.

Mini Reviews in Medicinal Chemistry
|May 29, 2003
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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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Commonly used fusion techniques — electroporation, polyethylene glycol...