Use of a human polymerized hemoglobin solution as an adjunct to acute normovolemic hemodilution during complex

Edward J Norris1, Paul M Ness, G Melville Williams

  • 1Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 212877, USA. enorris@jhmi.edu

Oxygen-carrying hemoglobin (Hb) solutions are under intense investigation as an alternative to allogeneic red cell transfusion during surgery, with or without acute normovolemic hemodilution. We present a case in which an investigational Hb solution was used as an adjunct to acute normovolemic hemodilution, and as a replacement for surgical blood loss in a patient undergoing complex aortic reconstruction with a large blood loss.