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Cerebrovascular diseases and depression.

Himani Ghoge1, Santvana Sharma, Shamash Sonawalla

  • 1Neuropsychiatry Clinic, Jaslok Hospital and Research Centre, 15 Dr B G Deshmukh Marg, Bombay 400 026, India. rajeshparikh@vsnl.com

Current Psychiatry Reports
|May 30, 2003
PubMed
Summary

Post-stroke depression is common within two years of a cerebrovascular accident, influenced by lesion location, especially near the left frontal pole. Comprehensive treatment is crucial for managing its psychological and physical effects.

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Area of Science:

  • Neurology
  • Psychiatry
  • Public Health

Background:

  • Cerebrovascular diseases are a major health concern.
  • Depression is the most frequent psychiatric condition following a stroke.
  • Post-stroke depression often manifests within two years of a cerebrovascular accident.

Purpose of the Study:

  • To review the association between cerebrovascular diseases and depression.
  • To highlight the impact of lesion location on post-stroke depression.
  • To discuss treatment modalities for post-stroke depression.

Main Methods:

  • Literature review of studies on cerebrovascular diseases and depression.
  • Analysis of factors associated with post-stroke depression, including lesion location, physical and cognitive impairments, and aphasia.

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  • Examination of treatment options such as pharmacotherapy, psychotherapy, electroconvulsive therapy, and rehabilitation.

    • Main Results:

    • Lesion location, particularly proximity to the left frontal pole, significantly affects the frequency and severity of post-stroke depression.
    • Physical impairment, cognitive deficits, and aphasia are associated with post-stroke depression.
    • Depression is the most common psychiatric disorder post-stroke.

    Conclusions:

    • Understanding the psychological and physical impact of post-stroke depression is vital.
    • Timely and comprehensive treatment strategies are essential for effective management.
    • Cerebrovascular disease management should integrate mental health considerations.