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[Castleman's disease located in the central nervous system]
E Delmont1, M Lonjon, J-F Michiels
1Service de Neurologie, CHU, Nice.
Revue Neurologique
|May 30, 2003
Summary
Castleman's disease, a rare lymphoproliferative disorder, can present as a solitary intracranial tumor. This case highlights the excellent prognosis of localized Castleman's disease following treatment.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Castleman's disease is a rare lymphoproliferative disorder.
- Intracranial involvement is an unusual presentation of Castleman's disease.
Observation:
- A 26-year-old woman presented with trigeminal neuralgia and ocular symptoms.
- Imaging revealed a paracavernal tumor that had progressed over three months.
Findings:
- Histopathological analysis after partial tumor resection confirmed Castleman's disease.
- The patient achieved a complete cure six months post-treatment with focal adjuvant radiotherapy.
Implications:
- Localized Castleman's disease, unlike the multifocal form, demonstrates an excellent prognosis.
- This case underscores the importance of considering Castleman's disease in the differential diagnosis of intracranial tumors.