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Meningioangiomatosis with predominantly cellular pattern.
Anastassios V Koutsopoulos1, Andreas Yannopoulos, Efstathios N Stathopoulos
1Department of Pathology, University Hospital of Crete, Herakleion, Greece. anastassioskoutsopoulos@hotmail.com
Summary
Meningioangiomatosis (MA) is a rare condition. This case study details a 10-year-old girl with refractory seizures successfully treated with surgical removal of a left frontal lobe MA lesion.
Area of Science:
- Neurology
- Neurosurgery
- Pediatric Neurology
Background:
- Meningioangiomatosis (MA) is a rare, benign, non-neoplastic proliferation of meningothelial and vascular elements.
- MA can present with neurological symptoms, including seizures, particularly in pediatric patients.
- Early diagnosis and surgical intervention are crucial for managing MA-related symptoms.
Observation:
- A 10-year-old girl presented with refractory complex partial and secondary generalized seizures since age 8.
- MRI revealed a left frontal lobe lesion consistent with MA.
- The patient underwent surgical lesionectomy for the MA.
Findings:
- Histopathological examination confirmed the lesion as meningioangiomatosis (MA).
- Postoperative follow-up at one year showed the patient to be symptom-free.
- The case highlights the importance of integrating imaging, histological, and immunohistochemical findings.
Implications:
- Surgical resection of meningioangiomatosis lesions can lead to complete seizure remission in pediatric patients.
- This case contributes to the understanding of MA presentation and management in children.
- Further research into the pathogenesis and optimal treatment strategies for MA is warranted.