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New treatments for serpiginous choroiditis
Esen Karamursel Akpek1, Ozge Ilhan-Sarac
1The Wilmer Eye Institute, 600 North Wolfe Street, Maumenee 321, Baltimore, MD 21287-9238, USA. esakpek@jhmi.edu
Current Opinion in Ophthalmology
|June 5, 2003
Summary
Serpiginous choroiditis, an inflammatory eye condition, can cause vision loss. This review covers recent advancements in managing this rare but serious disorder.
Area of Science:
- Ophthalmology
- Inflammatory diseases
Background:
- Serpiginous choroiditis is a rare, bilateral inflammatory condition affecting the inner choroid and retinal pigment epithelium.
- It presents with a distinctive retinal distribution and can lead to significant vision impairment.
Purpose of the Study:
- To review recent ophthalmic literature on the management of serpiginous choroiditis.
- To highlight current therapeutic strategies and their outcomes.
Main Methods:
- Systematic review of recent ophthalmic literature.
- Analysis of published studies on serpiginous choroiditis management.
Main Results:
- Recurrent inflammation and foveal involvement are key factors in vision loss.
- Choroidal neovascularization is a common complication.
- Recent literature focuses on immunomodulatory and anti-VEGF therapies.
Conclusions:
- Effective management of serpiginous choroiditis requires addressing inflammation and complications like neovascularization.
- Early and appropriate treatment is crucial to prevent permanent vision loss.