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Acute reductions in ventricular myocardial tissue velocities after direct current cardioversion of atrial
Kevin C Fung1, Hiok C Tan, Leonard Kritharides
1Department of Cardiology, University of Sydney, Concord Hospital, Hospital Road, Concord, NSW 2139, Australia.
Insights
Direct current (DC) cardioversion acutely reduces left ventricular velocity in patients with atrial fibrillation. This effect is reversible and subclinical, warranting further investigation into its clinical significance.
Area of Science:
- Cardiology
- Electrophysiology
- Echocardiography
Background:
- Direct current (DC) cardioversion can cause atrial stunning.
- Acute pulmonary edema is a reported complication of DC cardioversion.
- The impact of DC cardioversion on ventricular function is not well understood.
Purpose of the Study:
- To investigate the acute effects of DC cardioversion on myocardial velocity.
- To assess ventricular dysfunction using Doppler tissue imaging after DC cardioversion.
Main Methods:
- 40 patients (30 with atrial fibrillation, 10 with atrial flutter) underwent transthoracic echocardiography.
- Doppler tissue imaging assessed peak systolic velocity in 6 ventricular segments before and after DC cardioversion.
- Follow-up assessments were conducted after achieving sustained sinus rhythm.
Main Results:
- DC cardioversion significantly decreased peak systolic velocity in multiple ventricular segments in patients with atrial fibrillation.
- Left ventricular ejection fraction remained unchanged immediately after DC cardioversion.
- No significant changes in peak systolic velocity were observed in the atrial flutter group; all patients showed improved velocity upon follow-up.
Conclusions:
- DC cardioversion induces a subclinical, acute, and reversible reduction in left ventricular peak systolic velocity in atrial fibrillation patients.
- The clinical significance and underlying mechanisms of this reduction require further study.
Background:
Cardioversion by direct current (DC) and other methods can cause atrial "stunning." There are case reports of acute pulmonary edema after DC cardioversion, but whether acute ventricular dysfunction is a general consequence of DC cardioversion is unknown. We have investigated whether DC cardioversion acutely affects myocardial velocity assessed by Doppler tissue imaging.
Methods:
40 patients (30 with atrial fibrillation and 10 with atrial flutter) undergoing elective DC cardioversion underwent transthoracic echocardiography with Doppler tissue imaging before and immediately after cardioversion, and after follow-up. Peak systolic velocity was derived for 6 ventricular segments using Doppler tissue imaging.
Results:
Immediately after DC cardioversion of atrial fibrillation, peak systolic velocity decreased in basal lateral (4.3 +/- 2.0-3.3 +/- 1.7 cm/s, P <.001), mitral annulus-septal (3.8 +/- 1.0-3.5 +/- 0.9, P <.05), mitral annulus-lateral (4.9 +/- 1.6-4.1 +/- 1.7, P <.001), and tricuspid annular (7.8 +/- 2.0-7.0 +/- 1.2, P <.03) segments, even though left ventricular ejection fraction was unchanged. In contrast, for the atrial flutter group there were no significant changes in peak systolic velocity in any segment post-DC cardioversion. Follow up studies were performed after sustained in sinus rhythm in both atrial fibrillation and atrial flutter groups. For both groups, increased peak systolic velocity was found in all 6 segments on follow-up (all P <.05).
Conclusions:
DC cardioversion causes subclinical, acute reversible reduction in left ventricular peak systolic velocity in patients with atrial fibrillation. The causes of this reduction in myocardial contractile velocity and the circumstances in which acute dysfunction become clinically significant warrant further investigation.
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