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Updated: Jul 23, 2026

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
Male breast cancer
Objective:
To review cases of male breast cancer.
Settings:
Histopathology Section, Department of Pathology, The Aga Khan University, Karachi.
Method:
Fifty one cases of male breast cancer specimens, received during a period of 10 years, routinely processed and stained with Haematoxylin and Eosin were analyzed. Special stains and Immunohistochemistry were used in difficult cases.
Results:
Male breast cancer affected individuals in the sixth and seventh decades of life with a mean age of 56.2 years. Infiltrating ductal carcinoma (IDC) was the predominant type. Skin involvement was seen in 27.45% of the cases. Breast lump was the most common presenting symptom followed by skin ulceration. At the time of presentation 43.13% patients had a tumour size of more than 3 cm.
Conclusion:
Male breast cancer is a rare disease. Most of our findings correspond to the published local and international data.

