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Updated: Jul 23, 2026

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Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
Male breast cancer
Summary
Male breast cancer is rare, predominantly affecting men in their 50s and 60s. Infiltrating ductal carcinoma is the most common type, with breast lumps being the usual symptom.
Area of Science:
- Oncology
- Pathology
- Men's Health
Background:
- Male breast cancer is an uncommon malignancy.
- Understanding its characteristics is crucial for diagnosis and treatment.
Purpose of the Study:
- To review and analyze cases of male breast cancer.
- To describe the clinicopathological features of male breast cancer.
- To compare findings with existing local and international data.
Main Methods:
- Retrospective analysis of 51 male breast cancer specimens over 10 years.
- Routine processing and Hematoxylin and Eosin staining.
- Special stains and immunohistochemistry used for challenging cases.
Main Results:
- The disease primarily affects men in their sixth and seventh decades (mean age 56.2 years).
- Infiltrating ductal carcinoma (IDC) was the predominant histological type.
- Common symptoms included breast lump and skin ulceration, with 27.45% exhibiting skin involvement and 43.13% presenting with tumors >3 cm.
Conclusions:
- Male breast cancer is a rare condition.
- The observed clinicopathological features align with previously published data.
- Further research may aid in early detection and management strategies.

