Epithelioid haemangioendothelioma of the liver

Epithelioid haemangioendothelioma is a well-recognized vascular neoplasm but can be mistaken for metastatic adenocarcinoma or other primary liver tumors. We present a case of epithelioid haemangioendothelioma of the liver in a 62 year old woman, in whom the diagnosis was missed by various pathologists. This patient presented with loss of appetite and weight, and fever. She rapidly deteriorated and died presumably of liver cell failure. The characteristic histological features and the positive immunostaining for endothelial markers (CD31 & Ulex europaeus) confirmed the diagnosis.