Related Experiment Videos
Corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis
Maryam Zamani1, Richard A Garfinkel
1Department of Ophthalmology, George Washington University Hospital, (M.Z.), Washington, DC, USA.
Purpose:
To report a case of corticosteroid-induced modulation of acute syphilitic posterior placoid chorioretinitis.
Design:
Interventional case report.
Method:
A 38-year-old homosexual male who presented with a unilateral uveitis secondary to syphilis developed large placoid macular lesions after treatment with oral prednisone that resolved when the corticosteroids were discontinued.
Results:
A cause-and-effect relationship was demonstrated between oral prednisone and the appearance of acute syphilitic posterior placoid chorioretinitis.
Conclusions:
The clinical appearance of posterior placoid chorioretinitis in syphilis may be modulated by the immune status of the patient.