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Trypan blue-assisted peeling of the internal limiting membrane during macular hole surgery
1Ophthalmology Department, Centre Hospitalier Université de Montréal-Pavillon Notre-Dame, Montréal, Québec, Canada. perrier.manuel@sympatico.ca
Purpose:
To evaluate the outcome of surgeries for macular holes using trypan blue to facilitate delamination of the internal limiting membrane.
Design:
A retrospective series of 18 patients.
Method:
All patients underwent a three-port pars plana vitrectomy with internal limiting membrane delamination using trypan blue 0.06% to assist visualization. The main outcome measures were postoperative visual acuity and clinically evident retinal pigment epithelial changes.
Results:
The median preoperative visual acuity was 20/200, and the median postoperative visual acuity was 20/70. All but one macular hole were closed after surgery (94%). At the last recorded follow-up, 10 patients (56%) had improved visual acuity of at least two chart lines. No adverse reaction related to trypan blue was observed up to 1 year postsurgery.
Conclusions:
Trypan blue staining of internal limiting membrane may accomplish more complete dissections of the internal limiting membrane and better surgical and visual outcomes.