Renal angiomyolipoma: a clinico-pathological study or eleven cases

Retrospective analysis of clinical and histomorphological features and follow up of eleven cases of renal angiomyolipoma (AML) encountered during the past twelve years at our centre was performed. These included seven female and four male patients, nine of them were symptomatic and two were incidentally detected on ultrasonography for other reasons. Eight patients had solitary and three had bilateral lesions on radiological investigations. None of the three patients with bilateral AML had associated tuberous sclerosis, however, a patient with tuberous sclerosis, showing solitary lesion on radiological investigation, was detected to have multiple lesions on thorough pathological examination of the nephrectomy specimen. The surgical treatment comprised of nephrectomy in six cases, enucleation in four cases and trueut biopsy in one case. Enucleation of the largest lesion was done in all three patients of bilateral AML. The mean follow up was of three years. Two patients with bilateral AML had radiological progression of size of other lesions, whereas one died due to excessive bleeding in the postoperative period. None of the patients had any evidence of recurrence or metastasis. Bilateral AML is not always associated with tuberous sclerosis, however, in patients with tuberous sclerous thorough sampling of nephrectomy specimen is recommended.