Synthetic studies on ecteinascidin-743: constructing a versatile pentacyclic intermediate for the synthesis of
Wei Jin1, Sammy Metobo, Robert M Williams
1Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
Organic Letters
|June 7, 2003
Abstract:
[reaction: see text] The asymmetric synthesis of a highly functionalized pentacyclic tetrahydroisoquinoline relevant to the ecteinascidin, saframycin, safracin, and renieramycin family of antitumor alkaloids is described.


