An efficient and selective method for preparing glycosyl sulfoxides by oxidizing glycosyl sulfides with OXONE or
Ming-Yi Chen1, Laxmikant Narhari Patkar, Hui-Ting Chen
1Institute of Chemistry, Academia Sinica, 128, Sec. 2, Yen-Chiu-Yuan Rd. Nankang, 115, Taipei, Taiwan, ROC.
Carbohydrate Research
|June 7, 2003
Abstract:
Silica gel adsorbed with OXONE or t-BuOOH was used as a mild oxidant to selectively oxidize glycosyl sulfides to corresponding sulfoxides in good yields and without sulfones formation. This method was also found compatible with various other functional groups in the glycosides.
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